Research Tech III - Dr. Robert B. Wilson Lab

A research technician position is available in the laboratory of Dr. Robert B. Wilson in the Department of Pathology and Laboratory Medicine and the Center for Mitochondrial and Epigenomic Medicine at the Children’s Hospital of Philadelphia/University of Pennsylvania. Our laboratory studies mitochondrial disorders, focusing on Friedreich ataxia (FA), a progressive neuro- and cardio-degenerative disorder. Our lab is primarily translational: we are studying cellular pathways underlying FA pathophysiology with the goal of identifying and testing drugs and drug targets that might ameliorate the disease. To that end we have developed cell-based models of FA, including iPSC-derived sensory neurons and cardiomyocytes. We recently developed a zebrafish model of FA, which will allow us to extend our testing of pathways, drugs, and drug targets in a complex vertebrate organism. The candidate will focus primarily on further development of, and testing in, the zebrafish model as his or her project. The candidate will work closely with other members of the research team, both on the zebrafish project and on other projects, and will assist the research team in some administrative tasks such as ordering of reagents and supplies.

CHOP is an equal opportunity employer. CHOP employees are provided with comprehensive benefits package including eligible health insurance and retirement plans (http://www.research.chop.edu/careers/working-research/benefits-information). CHOP and UPenn offer excellent research and training environments. The lab is committed to the success and career development of every team member.

Recent publications include:

Cotticelli, M. G., Xia, S., Kaur, A., Lin, D., Wang, Y., Ruff, E., Tobias, J. W., Wilson, R. B.: Identification of p38 MAPK as a novel therapeutic target for Friedreich's ataxia. Scientific Reports 8(1): 5007, 2018.

Cotticelli, M. G., Xia, S., Lin, D., Lee, T., Lin, D., Terrab, L., Wipf, P., Huryn, D., Wilson, R. B.: Ferroptosis as a novel therapeutic target for Friedreich's ataxia. Journal of Pharmacology and Experimental Therapeutics 369: 47-54, 2019.

send resumes to kerwinj@chop.edu

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